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compound 19  (Selleck Chemicals)


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    Structured Review

    Selleck Chemicals compound 19
    Compound 19, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 1277 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/compound+19/Compound/bio_rxiv__64898__2025__12__16__694573-151-22-26
    Average 96 stars, based on 1277 article reviews
    compound 19 - by Bioz Stars, 2026-09
    96/100 stars

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    Related Articles

    other:

    Article Title: Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells
    Article Snippet: Compound 19 (VPS34 inhibitor 1) , Selleckchem , Cat#S8456.

    Article Title: SARS-CoV-2 envelope protein induces LC3 lipidation via the V-ATPase-ATG16L1 axis
    Article Snippet: Chemical reagents used in this study included monensin (Merck, M5273), bafilomycin A1 (Abcam, ab120497), Torin-1 (Selleckchem, S2827), Vps34 IN-1 compound 19 (Selleckchem, S8456), doxycycline (Sigma, D9891) and MG132 (Sigma, M7449).

    Article Title: LRRK2 is activated by phosphatidylinositol 3-phosphate in conjunction with CASM
    Article Snippet: The following reagents were used at final concentrations as indicated: apilimod (100 nM, MedChemExpress), YM203616 (5 μM, AdooQ), VPS34-IN1 (10 μM, Cayman), Compound 19 (50 μM, Selleck), chloroquine (50-100 μM, Sigma), monensin (50 μM, Cayman), nigericin (10 μM, Sigma), diphenyleneiodonium chloride (DPI, 10 μM, Selleck), zymosan (Sigma), bafilomycin A 1 (30 nM, Wako).

    Western Blot:

    Article Title: The V-ATPase/ATG16L1 axis is controlled by the V 1 H subunit
    Article Snippet: .. Antibodies used in this study were rabbit polyclonal anti-ATG5 (Cell Signalling Technology, 2630, WB 1:1000), rabbit monoclonal anti-ATG16L1 (Cell Signalling Technology, 8089, WB 1:1000), rabbit monoclonal anti-LC3B (Novus Biologicals, NBP2-46892, WB 1:1000), rabbit polyclonal anti-GABARAPL1 (Proteintech, 11010-1-AP, WB 1:1000), mouse monoclonal anti-IAV matrix 2 (Abcam, ab5416, WB 1:1000, IF 1:100), mouse monoclonal anti-β-actin (Proteintech, 66009-1, WB 1:10000), rabbit monoclonal anti-ATP6V1A (Abcam, ab199326, WB 1:1000), mouse monoclonal anti-ATP6V1B1/2 (Santa Cruz Biotechnology, sc-55544, WB 1:1000), rabbit monoclonal anti-ATP6V1D (Abcam, ab157458, WB 1:1000), rabbit polyclonal anti-ATP6V1E1 (Invitrogen, PA5-29899, WB 1:1000), rabbit polyclonal anti-ATP6V1H (Proteintech, 26683-1-AP, WB 1:1000), rabbit polyclonal anti-ATP6V0A1 (Proteintech, NBP1-89342, WB 1:1000), rabbit monoclonal anti-ATP6V0D1 (Abcam, ab202899, WB 1:1000), mouse monoclonal anti-FLAG (Sigma, F1804, WB 1:3000) and mouse monoclonal anti-Strep-tag-II (Abcam, ab184224, WB 1:1000) Chemical reagents used in this study included monensin (Merck, M5273), Vps34 IN-1 compound 19 (Selleckchem, S8456), bafilomycin A1 (Abcam, ab120497) and Torin-1 (Selleckchem, S2827). .. HEK293T (provided by Cell Services of the Francis Crick Institute) and ATG13 KO GFP-LC3B HEK293 cells (a kind gift from O. Florey) were cultured in Dulbecco’s modified Eagle’s medium (DMEM; GIBCO Life Technologies) containing 10% Fetal Calf Serum (FCS), GlutaMax (GIBCO Life Technologies) and Penicillin-Streptomycin (GIBCO Life Technologies).



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